Detection and Host Defense Pattern Recognition Molecules for Pathogen Domain-Like Receptors: Intracellular Nucleotide-Binding Oligomerization
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Nucleotide-binding oligomerization domain-like receptors: intracellular pattern recognition molecules for pathogen detection and host defense.
The nucleotide binding oligomerization domain-like receptor (NLR) family of pattern recognition molecules is involved in a diverse array of processes required for host immune responses against invading pathogens. Unlike TLRs that mediate extracellular recognition of microbes, several NLRs sense pathogens in the cytosol and upon activation induce host defense signaling pathways. Although TLRs an...
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تاریخ انتشار 2006